It used to make bank 💵 In the United States it was the highest selling medication between 19, selling more than two billion tablets in 1978 alone. By mouth, effects begin after 15 to 60 minutes.

Diazepam works fast 🏃 When given into a vein, effects begin in one to five minutes and last up to an hour. Order written to provide sedation during mechanical ventilation should be discontinued when patient is no longer receiving mechanical ventilation support.1.Central venous access preferred due to vein irritation (consider alternate benzodiazepine for IV use).Continuous infusions must be administered by infusion device and the pump library must be enabled.May be titrated by a nurse in Adult Critical Care.May be administered IV direct or by IV infusion by a nurse in Adult Critical Care.diazepam + other CNS depressants = increased sedation.adverse effects may be amplified in the presence of hepatic or renal failure.Central venous administration if possible. Ensure IV patency before and after administration. Inject into the tubing of a rapidly flowing IV as close as possible to site. TWithdrawal prolonged use of continuous benzodiazepines should be weanedĭiazepam is a vesicant and may cause thrombophlebitis, or progressive and severe tissue injury.Slurred speech, ataxia, impaired coordination.Headache, confusion, drowsiness, dizziness, excessive sedation.Respiratory depression and partial airway obstruction, especially when combined with narcotics or during rapid administration.Known hypersensitivity to diazepam or its components.Respiratory depression and partial airway obstruction, especially when combined with narcotics or in patients with hypercarbic respiratory disease.Conflicting data about diazepam's solubility and stability in an infusion, therefore not recommended.Rate of administration should not exceed 5 mg/min.intervals (up to 30 mg in an 8-hour period) Anticonvulsant: 5-10 mg IV which may be repeated at 10 - 15 min.Alcohol withdrawal: 5-20 mg IV repeated as needed (intervals from 5 minutes to 4 hours).Anxiolytic, sedative: 2-5 mg IV (moderate anxiety).Muscle relaxant - useful in patient with tetanus.Useful in the management of alcohol withdrawal and delirium tremens.Has no long-term anticonvulsant activity.Used in the initial control of seizures or in the treatment of status epilepticus.Anxiolytic agent sedative anticonvulsant:

Diazepam antidote